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KMID : 1007520230320040471
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Food Science and Biotechnology
2023 Volume.32 No. 4 p.471 ~ p.480
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Breast milk from healthy women has higher anti-Candida properties than women with vaginal infections during pregnancy
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Azka Ainun Nisaa
Chern-Ein Oon
Sasidharan Sreenivasan
Venugopal Balakrishnan
Jun Jie Tan
Cindy Shuan-Ju Teh
Salina Sany
Svetoslav Dimitrov Todorov
Guoxia Liu
Park Yong-Ha
Min-Tze Lion
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Abstract
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The aim of this study was to investigate the different immunological and antimicrobial properties of breast milk from women with (W) or without (WO) vaginal yeast infections during pregnancy in 85 lactating women (W, n?=?43; WO, n?=?42). Concentrations of IL-10, IgA, IgM, IgG, EGF, and TGF-α were similar in both groups. However, breast milk of women aged below 31 years old from the W-group showed higher concentration of EGF than the WO-group (p?=?0.031). Breast milk from WO-group exhibited higher anti-Candida properties than W-group, both via growth inhibition and aggregation of yeast cells (p?
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KEYWORD
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Breast milk, Vaginal infections, Pregnant women, Immuno-modulation, Anti-Candida
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